Hubei, China
Export Year:
2004-04-15
Main Markets:
North America, Europe
Terms of Payment:
T/T, Western Union
OEM/ODM Service
Sample Available

Gw 610742, CAS: 317318-84-6, Pharmaceutical Chemical manufacturer / supplier in China, offering Hot Sale Low Price Gw 610742 Sarm Obesity Treatment Powder, Muscle Growth Chemical Powder Gonadorelin with Top Quality, Fema Let Powder Anti Estrogen for Breast Cancer and so on.

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Supplier Homepage Products Other pharmaceutical materials Hot Sale Low Price Gw 610742 Sarm Obesity Treatment Powder

Hot Sale Low Price Gw 610742 Sarm Obesity Treatment Powder

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Min. Order / Reference FOB Price
1 G US $1/ G
Port: Wuhan, China
Production Capacity: 1000kg/Month
Payment Terms: Western Union, Paypal, Money Gram, Cash,Bank wire transfer,bitcoin
Powder: Yes
Customized: Non-Customized
Certification: GMP
Description: White or Almost White Crystalline Powder
Assay: 99%
Transport Package: Different Kinds of Special Packing Methods.

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Basic Info

Model NO.
CAS: 317318-84-6
Trademark
ZK
Specification
USP EP CP BP
Origin
China
Quick detail:
Product Name: GW-0742
Other Name: GW610742
Purity:99%min by HPLC
CAS No.: 317318-84-6
Formula:C21H17F4NO3S2
Exact Mass:471.05900
Molecular Weight:471.48800
PSA:112.96000
LogP:6.34050
Appearance: White fine powder

Description:
GW0742 is a high affinity PPAR-β/δ agonist reduces lung inflammation induced by bleomycin instillation in mice.
A high throughput screening campaign was conducted to identify small molecules with the ability to inhibit the interaction between the vitamin D receptor (VDR) and steroid receptor coactivator 2. These inhibitors represent novel molecular probes to modulate gene regulation mediated by VDR. The peroxisome proliferator-activated receptor δ (PPARδ) agonist GW0742 was among the identified VDR-coactivator inhibitors and has been characterized herein as a pan nuclear receptor antagonist at concentrations higher than 12.1 µM. The highest antagonist activity for GW0742 was found for VDR and the androgen receptor (AR). Surprisingly, GW0742 behaved as PPAR agonist/antagonist activating transcription at lower concentration and inhibiting this effect at higher concentrations. A unique spectroscopic property of GW0742 was identified as well. In the presence of rhodamine-derived molecules, GW0742+ increased fluorescence intensity and fluorescence polarization at an excitation wavelength of 595 nm and emission wavelength of 615 nm in a dose dependent manner. The GW0742-inhibited NR-coactivator binding resulted in a reduced expression of five different NR target genes in LNCaP cells in the presence of agonist. Especially VDR target genes CYP24A1, IGFBP-3 and TRPV6 were negatively regulated by GW0742. GW0742 is the first VDR ligand inhibitor lacking the secosteroid structure of VDR ligand antagonists. Nevertheless, the VDR-meditated downstream process of cell differentiation was antagonized by GW0742 in HL-60 cells that were pretreated with the endogenous VDR agonist 1,25-dihydroxyvitamin D3.

MK677 Nutrobal Ibutamore,MK-2866 Ostarine,AICAR Acadesine:
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LGD-4033 Ligandrol,Andarine S4,GW501516 Cardarine:
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SR9009 Stenabolic,RAD140 Testolone,YK11:
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S23,AC 262356,SR9011,GW-0742:
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Product list:
Anabolics TesCypionate
TesEnanthate
TesPropionate
TesDecano
TesAcetate
 
Sus250
TesPhenylpropionate
TesIsocaproate
TesUndecano
TesBase
 
Oxan / Ana
Oxy/ Anad
 
Metan / Dian
Stan / wins
 
TreAcetate
TreEnanthate
TreHexahydrobenzyl carbonate
TreBase
 
DrosPropionate / MastPropionate
DrosEnanthate / MastEnanthate
MethAcetate / PrimAcetate
MethEnanthate / PrimEnanthate
Fluoxy/ Halot
Mester/ Provi
17alpha-Methyl-1-tes
Methyltes
17alpha-Methyl-Dro/ Super
 
4-Chlorotescetate/ClostAcetate
Epiandrost
Dehydroepiandrost
7-Keto-dehydroepiandrost
4Chlorodehydromethyltes/oral turi
NandDecan
NandPhenylpropionate
 
Nand Base
NandCypionate
NandUndecylate
BoldUndecano/ Equi
BoldeAcetate
 
BoldBase
BoldCypionate
BoldPropionate
 Sild/via
Dutasterid / Avodar
Finasterid / Prosca
 
TadaCitrate / Cia
Vard /Levi
Dapo / Pril
Yohimbine Hydrochloride / Corynine / Aphrodine
Anti-EstrogenTamoCitrate / Nolvx
ClomCitrate / Clo
Letr
Anas / Arim
Exem/Arom
T3 /Cytomel /Liothyronine sodium
T4 /L-Thyroxine /tetraiodothyronine
GH &PeptidesGH
CG
GH raw powder
MT2 raw powder
Ghrp2 raw powder
GHrp6 raw powder
Cjc 1295 raw powder
IFG-1(1-3)
GF-1 LR3
GH fragment176-191
CJC-1295
CJG-1295DAC
GHRP-6
GHRP-2
MGF
 
PEG-MGF
Ipamorelin
Sermorelin
Gonadorelin
Tesamorelin
TB-500
Selank
DISP
PT-141
Melanotan1
Melanotan2
Epithalon
Myostatin
Follistatin
ACE-031
HMG
SarmsMK-677/Nutrobal / Ibutamore
MK-2866 /Ostarine
LGD-4033 /Anabolicum
SR9009
GW 501516 /Cardarine
S-4 /Andarine
 
S-23
RAD-140
YK-11
AICAR
GW 0742
SR9011
AC262356
Local AnaestheticBenzocaine
Benzocain HCL
Lidocaine
Lidocaine HCL
 
Tetracaine
Tetracaine HCL
Procaine
Procaine HCL
Weight lossT3 / Liothyronine sodium
T4 / L-Thyroxine
GH
L (-) -Carnitine
L-Carnitine-L-Tartrate
SARMS

Our advantages: 
1. Top quality and factory price,a discount would be given when you make a large order.
2. Rich experienced in delivering,package will be reshipped if sent failed. 
3. Enough GW-0742 stock ensure the prompt delivery time. 
4. Good after-sales service,any of your question would be solved for the first as soon as possible.
5. Adhering to the principle of customer first conviction,we will provide the best and the most sincere services as possible as we can. 
 

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